INT162811

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.71
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.61
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Camk2a) kinase activity (Camk2a) cytoplasm (Camk2a)
Anatomy Link Frequency
pyramidal neurons 1
amacrine cells 1
nucleus 1
ganglion cells 1
Camk2a (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 3 99.80 Very High Very High Very High
Hippocampus 3 99.54 Very High Very High Very High
Pyramidal cell 1 97.12 Very High Very High Very High
Morphine 4 96.48 Very High Very High Very High
nMDA receptor 54 94.36 High High
addiction 37 84.52 Quite High
Opioid 3 84.12 Quite High
Neurotransmitter 6 50.96 Quite High
Glutamate receptor 14 50.00 Quite Low
Glutamate 16 18.16 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 34 98.56 Very High Very High Very High
Urological Neuroanatomy 1 89.40 High High
Opiate Addiction 3 84.52 Quite High
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Diphtheria 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the cortex, hippocampus and amygdala, KLC1 co-localized with calcium/calmodulin-dependent protein kinase II (CaMKII), suggesting that KLC1 was present in the cell bodies and dendrites of pyramidal neurons.
Localization (localized) of CaMKII in pyramidal neurons associated with pyramidal cell, hippocampus and amygdala
1) Confidence 0.71 Published 2009 Journal Eur. J. Neurosci. Section Abstract Doc Link 19735294 Disease Relevance 0.24 Pain Relevance 1.00
We have previously reported that retinal CaMKII mRNA, protein and enzyme activity (localized in the somas of amacrine cells and ganglion cells and in the inner plexifom layer) but not PKC?
Localization (localized) of CaMKII mRNA in ganglion cells associated with ganglion cysts
2) Confidence 0.64 Published 2001 Journal BMC Neurosci Section Body Doc Link PMC32198 Disease Relevance 0.18 Pain Relevance 0.15
In line with local Ca2+ sensing, pCaMKII puncta appeared at or near the cell surface but did not translocate to the nucleus.
Neg (not) Localization (translocate) of pCaMKII in nucleus
3) Confidence 0.45 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2592819 Disease Relevance 0 Pain Relevance 0.03
Recruitment of CaMKII as a steeply nonlinear reporter of channel activity
Localization (Recruitment) of CaMKII
4) Confidence 0.42 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2592819 Disease Relevance 0 Pain Relevance 0.09
We have previously reported that retinal CaMKII mRNA, protein and enzyme activity (localized in the somas of amacrine cells and ganglion cells and in the inner plexifom layer) but not PKC?
Localization (localized) of CaMKII mRNA in amacrine cells associated with ganglion cysts
5) Confidence 0.22 Published 2001 Journal BMC Neurosci Section Body Doc Link PMC32198 Disease Relevance 0.18 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox