INT162831

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 6.17
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lysosome (ARSD)
Anatomy Link Frequency
vertex 2
superior 1
neural 1
ARSD (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 3 100.00 Very High Very High Very High
imagery 183 99.78 Very High Very High Very High
addiction 7 96.16 Very High Very High Very High
Anterior cingulate cortex 581 95.80 Very High Very High Very High
drug abuse 15 95.60 Very High Very High Very High
Autonomic response 7 87.24 High High
Neurobehavioral 19 86.48 High High
fluoxetine 9 85.24 High High
sSRI 4 80.16 Quite High
alcohol 13 73.88 Quite High
Disease Link Frequency Relevance Heat
Schizophrenia 49 100.00 Very High Very High Very High
Cv General 2 Under Development 42 100.00 Very High Very High Very High
Headache 3 100.00 Very High Very High Very High
Ventricular Heart Septal Defects 2 99.84 Very High Very High Very High
Handedness 21 98.88 Very High Very High Very High
Patent Foramen Ovale 27 96.68 Very High Very High Very High
Autism 157 95.84 Very High Very High Very High
Drug Dependence 15 95.60 Very High Very High Very High
Toxicity 2 94.40 High High
Attention Deficit Hyperactivity Disorder 45 89.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The only other significant group difference in cortical activation was a less differentiated response for ASD participants to error versus correct responses in the medial aspect of the right superior frontal gyrus.
Regulation (response) of ASD in superior
1) Confidence 0.35 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0 Pain Relevance 0
An important consideration in interpreting this relation of FA to repetition is that subgenual rACC region was not functionally or structurally abnormal in this ASD sample.
Neg (not) Regulation (abnormal) of ASD
2) Confidence 0.35 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0.20 Pain Relevance 0.12
DTI data were acquired on all 12 ASD participants and 12 of the 14 controls.


Regulation (acquired) of ASD associated with imagery
3) Confidence 0.35 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0.38 Pain Relevance 0.05
These differences argue for distinct behavioural and neural signatures of response monitoring deficits in schizophrenia and ASD.
Regulation (argue) of ASD in neural associated with schizophrenia
4) Confidence 0.35 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0.93 Pain Relevance 0.13
ASD and control groups were matched for age, sex, handedness as measured by a laterality score on the modified Edinburgh Handedness Inventory (scores of ?
Regulation (groups) of ASD associated with handedness
5) Confidence 0.35 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 1.12 Pain Relevance 0.21
Devices approved for ASD or ventricular septal defect closure, however, are widely used off-label to close PFO in high-risk patients who, hopefully, have been appropriately counseled about the current state of evidence and the alternatives.
Regulation (approved) of ASD associated with patent foramen ovale, cv general 2 under development and ventricular heart septal defects
6) Confidence 0.29 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2948406 Disease Relevance 1.32 Pain Relevance 0
In fact, the size of an ASD has been found to change significantly during different phases of the cardiac cycle - by as much as an 86% change in area in some patients [8-10].
Regulation (change) of ASD associated with cv general 2 under development
7) Confidence 0.29 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2948406 Disease Relevance 0.43 Pain Relevance 0
We prospectively evaluated the effect of percutaneous ASD closure on migraine
Regulation (effect) of ASD associated with cv general 2 under development and migraine
8) Confidence 0.26 Published 2009 Journal Catheter Cardiovasc Interv Section Abstract Doc Link 19739264 Disease Relevance 0.73 Pain Relevance 0.27
Scatter plot shows BOLD signal from the maximum vertex in right rACC for each ASD participant on the y-axis and ADI-R score on the x-axis.
Regulation (participant) of ASD in vertex
9) Confidence 0.21 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0 Pain Relevance 0.14
Scatter plot shows FA from the maximum vertex in left rACC for each ASD participant on the y-axis and ADI-R score on the x-axis.
Regulation (participant) of ASD in vertex
10) Confidence 0.21 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0.07 Pain Relevance 0.11
Even when the pooled arrays of the Schweitzer study, which obviously have a smaller ARSD, are included the ARSD values are within two standard deviations of the mean ARSD.
Regulation (values) of ARSD
11) Confidence 0.04 Published 2006 Journal BMC Bioinformatics Section Body Doc Link PMC1523219 Disease Relevance 0 Pain Relevance 0
As shown in Table 1, the ARSD values of both biopsy studies are within two standard deviations of the mean ARSD.
Regulation (values) of ARSD
12) Confidence 0.04 Published 2006 Journal BMC Bioinformatics Section Body Doc Link PMC1523219 Disease Relevance 0 Pain Relevance 0
Prevalence, genetic, exposure, and pathophysiological evidence all suggest a role for environmental factors in the inception and lifelong modulation of ASD.
Regulation (modulation) of ASD
13) Confidence 0.03 Published 2010 Journal Interdisciplinary Toxicology Section Body Doc Link PMC2984125 Disease Relevance 1.01 Pain Relevance 0.15

General Comments

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