INT16286

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Context Info
Confidence 0.60
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 4.04
Pain Relevance 2.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (GHR) extracellular space (GHR) extracellular region (GHR)
plasma membrane (GHR) nucleus (GHR) cytoplasm (GHR)
Anatomy Link Frequency
follicle 2
limb 1
central nervous system 1
GHR (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 1 100.00 Very High Very High Very High
Paracetamol 12 97.00 Very High Very High Very High
transdermal 4 96.12 Very High Very High Very High
headache 4 94.88 High High
Central nervous system 3 94.84 High High
lidocaine 1 81.28 Quite High
Somatostatin 3 71.04 Quite High
Clonidine 5 66.56 Quite High
agonist 6 62.96 Quite High
narcan 6 60.80 Quite High
Disease Link Frequency Relevance Heat
Leukocytosis 1 99.88 Very High Very High Very High
Volume Depletion And Dehydration 3 99.00 Very High Very High Very High
Obesity 15 98.24 Very High Very High Very High
Ehrlichiosis 4 97.48 Very High Very High Very High
Shock 1 97.04 Very High Very High Very High
Vomiting 3 96.04 Very High Very High Very High
Increased Venous Pressure Under Development 1 95.84 Very High Very High Very High
Exanthema 1 95.72 Very High Very High Very High
Dizziness 1 95.32 Very High Very High Very High
Headache 4 94.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our patient, changes in mental status, upper motor neuron signs, cerebrospinal fluid pleocytosis, and increased serum protein levels were found in association with serologically confirmed ehrlichiosis and were most likely due to vasculitis involving the central nervous system.
Positive_regulation (increased) of serum protein in central nervous system associated with leukocytosis, ehrlichiosis, central nervous system and increased venous pressure under development
1) Confidence 0.60 Published 1990 Journal South. Med. J. Section Abstract Doc Link 2237570 Disease Relevance 1.01 Pain Relevance 0.14
As for the peripheral limb of the GH-insulin-like growth factor I (IGF-I) axis, high free IGF-I, low IGF-binding proteins 1 (IGFBP-1) and 2 (IGFBP-2), normal or high IGFBP-3 and increased GH binding protein (GHBP) circulating levels have been described in obesity.
Positive_regulation (increased) of GHBP in limb associated with obesity
2) Confidence 0.35 Published 1999 Journal Int. J. Obes. Relat. Metab. Disord. Section Abstract Doc Link 10193871 Disease Relevance 0.76 Pain Relevance 0.13
The severe dehydration of these workers was demonstrated by substantial increases in their hematocrit, serum protein, urea, creatinine, uric acid and electrolyte imbalance.
Positive_regulation (increases) of serum protein associated with volume depletion and dehydration
3) Confidence 0.31 Published 1991 Journal Pol J Occup Med Environ Health Section Abstract Doc Link 1819340 Disease Relevance 0.95 Pain Relevance 0.09
A subset of 14 of these patients (height more than 2.5 SD below mean, normal GH secretion, IGF-1 levels more than 2 SD below the mean, and serum concentrations of GHBP more than 2 SD below the mean) were further studied.63 Of the 14 patients, four had mutations in the GH receptor (none of the 24 control subjects had mutations).
Positive_regulation (concentrations) of GHBP
4) Confidence 0.29 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2898102 Disease Relevance 0.34 Pain Relevance 0
Total serum protein level (g/100ml) significantly increased following caffeination as well as during co-administration of caffeinated paracetamol and Vitamin E; and significantly decreased during co-administration of paracetamol and vitamin A.
Positive_regulation (increased) of serum protein associated with paracetamol
5) Confidence 0.00 Published 2007 Journal Niger J Physiol Sci Section Abstract Doc Link 18379621 Disease Relevance 0.07 Pain Relevance 1.01
Before and after 1, 2 and 3 months of therapy, the following circulating steroid and protein hormone levels were evaluated: DHEA, DHEAS, androstenedione, testosterone, estrone, estradiol, 17-hydroxyprogesterone, sex hormone-binding globulin (SHBG), follicle-stimulating hormone (FSH), luteinizing hormone (LH), beta-endorphin, growth hormone (GH) and cortisol, and a Kupperman score was performed.
Positive_regulation (following) of protein hormone in follicle
6) Confidence 0.00 Published 1999 Journal Gynecol. Endocrinol. Section Abstract Doc Link 10368794 Disease Relevance 0.06 Pain Relevance 0.40
Before and after 1, 2 and 3 months of therapy, the following circulating steroid and protein hormone levels were evaluated: DHEA, DHEAS, androstenedione, testosterone, estrone, estradiol, 17-hydroxyprogesterone, sex hormone-binding globulin (SHBG), follicle-stimulating hormone (FSH), luteinizing hormone (LH), beta-endorphin, growth hormone (GH) and cortisol, and a Kupperman score was performed.
Positive_regulation (circulating) of protein hormone in follicle
7) Confidence 0.00 Published 1999 Journal Gynecol. Endocrinol. Section Abstract Doc Link 10368794 Disease Relevance 0.06 Pain Relevance 0.40
Serum protein, albumin, fibrinogen, antithrombin III, alpha 1-fetoprotein concentrations, serum activities of cholinesterase and glutamate dehydrogenase, activated partial thromboplastin time and prothrombin time were normal in all patients.
Positive_regulation (activated) of Serum protein associated with glutamate
8) Confidence 0.00 Published 1996 Journal Digestion Section Abstract Doc Link 8739089 Disease Relevance 0.79 Pain Relevance 0.13

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