INT162995

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ephb1, Ppm1e) endosome (Ephb1) signal transduction (Ephb1)
nucleolus (Ppm1e) nucleus (Ppm1e) plasma membrane (Ephb1)
Ephb1 (Rattus norvegicus)
Ppm1e (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 7 98.44 Very High Very High Very High
Dopamine 1 89.08 High High
withdrawal 1 84.24 Quite High
opiate 1 81.72 Quite High
Disease Link Frequency Relevance Heat
Death 1 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At SW 3, p-PEA-15, a FADD-ERK binding partner, was also upregulated (51%) as well as the activation of its phosphorylating Akt1 kinase (49%).
Positive_regulation (upregulated) of ERK Binding (binding) of partner
1) Confidence 0.04 Published 2010 Journal Eur Neuropsychopharmacol Section Abstract Doc Link 19758790 Disease Relevance 0.06 Pain Relevance 0.74

General Comments

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