INT163037

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (E2f1) nucleus (E2f1) DNA binding (E2f1)
transcription factor binding (E2f1) cytoplasm (E2f1)
E2f1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 4 99.68 Very High Very High Very High
narcan 1 78.56 Quite High
antagonist 1 76.80 Quite High
mu opioid receptor 1 75.00 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With morphine treatment, the levels of both cytoplasmic and nuclear E2F1 which is the downstream effecter of AKT were elevated and the interaction of E2F1 with YY1, rather than Sp1, was also increased.
Positive_regulation (elevated) of Gene_expression (levels) of E2F1 associated with morphine
1) Confidence 0.11 Published 2010 Journal Biochem. Pharmacol. Section Abstract Doc Link 19765550 Disease Relevance 0 Pain Relevance 0.44

General Comments

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