INT16304

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.51
First Reported 1984
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 2.56
Pain Relevance 4.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GHRH) extracellular region (GHRH) cell-cell signaling (GHRH)
Anatomy Link Frequency
plasma 4
urine 2
GHRH (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 34 100.00 Very High Very High Very High
narcan 8 100.00 Very High Very High Very High
qutenza 10 99.98 Very High Very High Very High
opiate 3 95.24 Very High Very High Very High
headache 1 90.48 High High
antagonist 3 84.00 Quite High
agonist 2 81.52 Quite High
Somatostatin 2 76.40 Quite High
depression 6 75.00 Quite High
Enkephalin 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Thyroid Disease 8 100.00 Very High Very High Very High
Hypertension 3 99.84 Very High Very High Very High
Depression 8 90.56 High High
Headache 1 90.48 High High
Pressure And Volume Under Development 1 89.96 High High
Xerostomia 1 79.00 Quite High
Heart Rate Under Development 1 78.52 Quite High
Pressure Volume 2 Under Development 1 78.00 Quite High
Diuresis 3 76.48 Quite High
Acromegaly 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a mean 59% inhibition of the clonidine-induced peak elevation of plasma growth hormone was observed (p less than 0.05).
Negative_regulation (inhibition) of Positive_regulation (elevation) of growth hormone in plasma associated with clonidine
1) Confidence 0.51 Published 1989 Journal Clin. Pharmacol. Ther. Section Abstract Doc Link 2568210 Disease Relevance 0.24 Pain Relevance 0.77
Patients with hyperthyroidism have reduced growth hormone (GH) responses to pharmacological stimuli and reduced spontaneous nocturnal GH secretion.
Negative_regulation (reduced) of Positive_regulation (responses) of growth hormone associated with thyroid disease
2) Confidence 0.43 Published 1991 Journal Horm. Res. Section Abstract Doc Link 1823078 Disease Relevance 0.51 Pain Relevance 0.24
Our data demonstrate that the GH responses to clonidine as well as to GHRH in patients with hyperthyroidism are inhibited in a similar fashion with respect to normal subjects.
Negative_regulation (inhibited) of Positive_regulation (responses) of GHRH associated with thyroid disease and clonidine
3) Confidence 0.43 Published 1991 Journal Horm. Res. Section Abstract Doc Link 1823078 Disease Relevance 0.49 Pain Relevance 0.62
Compared to controls, depressed patients showed a significant attenuation of net growth hormone (GH) responses to GHRH associated with normal basal GH concentrations.
Negative_regulation (attenuation) of Positive_regulation (responses) of net growth hormone
4) Confidence 0.42 Published 1988 Journal Psychiatry Res Section Abstract Doc Link 3141943 Disease Relevance 0.23 Pain Relevance 0.29
Compared to controls, depressed patients showed a significant attenuation of net growth hormone (GH) responses to GHRH associated with normal basal GH concentrations.
Negative_regulation (attenuation) of Positive_regulation (responses) of GHRH
5) Confidence 0.42 Published 1988 Journal Psychiatry Res Section Abstract Doc Link 3141943 Disease Relevance 0.23 Pain Relevance 0.29
With chronic therapy, 24-h mean levels were significantly suppressed, and the GH stimulability of thyrotrophin-releasing hormone and growth-hormone-releasing hormone (pl-44) was markedly reduced.
Negative_regulation (reduced) of Positive_regulation (stimulability) of growth-hormone-releasing hormone
6) Confidence 0.41 Published 1986 Journal Scand. J. Gastroenterol. Suppl. Section Abstract Doc Link 2876499 Disease Relevance 0.26 Pain Relevance 0.13
Installation of saline solution containing 10 microM capsaicin produced a significant increase of mean urine output, an increase of GRF, of EPRF and of [Na+] and [K+] urine concentration.
Negative_regulation (produced) of Positive_regulation (increase) of GRF in urine associated with qutenza
7) Confidence 0.41 Published 1995 Journal Scand. J. Urol. Nephrol. Section Abstract Doc Link 7618049 Disease Relevance 0.43 Pain Relevance 0.70
Exogenous growth hormone (hGH) administration in humans attenuates the endogenous growth hormone (GH) response to some pharmacological stimuli; in particular, pretreatment with hGH completely blocks the serum GH response to growth hormone-releasing hormone.
Negative_regulation (attenuates) of Positive_regulation (response) of endogenous growth hormone
8) Confidence 0.37 Published 1996 Journal Eur. J. Endocrinol. Section Abstract Doc Link 8590960 Disease Relevance 0 Pain Relevance 0.15
Partial blockade by naloxone of clonidine-induced increase in plasma growth hormone in hypertensive patients.
Negative_regulation (blockade) of Positive_regulation (increase) of growth hormone in plasma associated with hypertension, narcan and clonidine
9) Confidence 0.12 Published 1984 Journal J. Clin. Endocrinol. Metab. Section Title Doc Link 6319449 Disease Relevance 0.19 Pain Relevance 1.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox