INT163062

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (IDH2) small molecule metabolic process (IDH2) oxidoreductase activity (IDH2)
carbohydrate metabolic process (IDH2)
IDH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
backache 1 85.72 High High
imagery 1 71.96 Quite High
Chronic low back pain 1 65.08 Quite High
Disease Link Frequency Relevance Heat
Back Pain 1 85.72 High High
Ochronosis 1 84.36 Quite High
Alkaptonuria 2 83.88 Quite High
Low Back Pain 1 65.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
So far, there is no proven treatment; but preclinical and phase I data with nitisinone, an inhibitor of HGA formation, are promising.
Negative_regulation (inhibitor) of HGA Binding (formation) of
1) Confidence 0.37 Published 2010 Journal Metab. Clin. Exp. Section Abstract Doc Link 19765774 Disease Relevance 0.40 Pain Relevance 0.19

General Comments

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