INT163096

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.16
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tlr2, VEGFA) extracellular space (VEGFA) growth (VEGFA)
extracellular region (VEGFA) proteinaceous extracellular matrix (VEGFA) plasma membrane (Tlr2)
Anatomy Link Frequency
dental pulp 2
Tlr2 (Rattus norvegicus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 86.12 High High
pulpitis 2 80.32 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 86.12 High High
Pulpitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The hypothesis underlying this study was that LTA induces VEGF expression in dental pulp cells through TLR2 and PI3k/Akt signaling.
TLR2 Positive_regulation (induces) of Gene_expression (expression) of VEGF in dental pulp
1) Confidence 0.07 Published 2009 Journal J. Dent. Res. Section Abstract Doc Link 19767581 Disease Relevance 0.09 Pain Relevance 0.09
These studies demonstrated that TLR2 signaling through the PI3K-Akt pathway is necessary for LTA-induced VEGF expression in pulp cells.
TLR2 Positive_regulation (necessary) of Gene_expression (expression) of VEGF
2) Confidence 0.07 Published 2009 Journal J. Dent. Res. Section Abstract Doc Link 19767581 Disease Relevance 0.07 Pain Relevance 0.12

General Comments

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