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Context Info
Confidence 0.57
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.13
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Crot) mitochondrion (Crot) peroxisome (Crot)
transferase activity, transferring acyl groups (Crot) lipid metabolic process (Crot)
Crot (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chronic opioid therapy 5 100.00 Very High Very High Very High
methadone 1 99.64 Very High Very High Very High
Opioid 6 99.62 Very High Very High Very High
Opioid rotation 1 92.96 High High
chronic noncancer pain 3 87.88 High High
Pain 5 84.20 Quite High
Breakthrough pain 1 83.96 Quite High
addiction 1 81.20 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 8 97.96 Very High Very High Very High
Postoperative Complications 2 94.40 High High
Pain 8 87.88 High High
Intraoperative Complications 3 85.52 High High
Heart Rate Under Development 1 81.52 Quite High
Opiate Addiction 1 80.76 Quite High
Mediastinal Emphysema 2 50.00 Quite Low
Mandibular Fractures 1 30.88 Quite Low
Infection 1 25.16 Quite Low
Emergencies 9 7.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This article summarizes key clinical messages from this guideline regarding patient selection and risk stratification, informed consent and opioid management plans, initiation and titration of COT, use of methadone, monitoring of patients, use of opioids in high-risk patients, assessment of aberrant drug-related behaviors, dose escalations and high-dose opioid therapy, opioid rotation, indications for discontinuation of therapy, prevention and management of opioid-related adverse effects, driving and work safety, identifying a medical home and when to obtain consultation, and management of breakthrough pain.
Gene_expression (initiation) of COT associated with pain, methadone, breakthrough pain, chronic opioid therapy, opioid and opioid rotation
1) Confidence 0.57 Published 2009 Journal Pol. Arch. Med. Wewn. Section Abstract Doc Link 19776687 Disease Relevance 0.72 Pain Relevance 1.82
Comparison of elective COT with PCT
Gene_expression (elective) of COT
2) Confidence 0.09 Published 2008 Journal Oral Maxillofac Surg Section Body Doc Link PMC2668591 Disease Relevance 0.42 Pain Relevance 0

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