INT163188

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Context Info
Confidence 0.62
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 1.27
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 3
joint 2
Cd19 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 1 69.44 Quite High
cytokine 80 58.80 Quite High
spinal inflammation 10 50.00 Quite Low
agonist 3 50.00 Quite Low
Cauda equina syndrome 1 9.36 Low Low
Sciatica 3 5.40 Low Low
Inflammation 33 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 11 98.12 Very High Very High Very High
Targeted Disruption 44 90.84 High High
Infection 197 87.80 High High
Sprains And Strains 7 82.84 Quite High
Splenomegaly 9 66.56 Quite High
Retroviridae Infections 1 62.40 Quite High
Cancer 14 50.00 Quite Low
Necrosis 7 50.00 Quite Low
Hematological Disease 19 46.08 Quite Low
Spinal Fractures 4 32.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The frequency of unsorted and CD19+ splenocytes recovered from I?
Localization (splenocytes) of CD19
1) Confidence 0.62 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1781481 Disease Relevance 0.18 Pain Relevance 0
Unsorted and CD19+ B cells were plated for ex vivo reactivation analyses at 16 dpi.
Localization (Unsorted) of CD19 in B cells
2) Confidence 0.62 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1781481 Disease Relevance 0.30 Pain Relevance 0
METHODS: We detected the proportions of CD19(+) B-cell, naive B-cell (CD19(+)CD27-), memory B-cell (CD19(+)CD27dim) and plasmablast (CD19(+)CD27high) in peripheral blood of 66 patients with AS (39 at active stage, 27 at stable stage; 35 patients with peripheral joint involvement, 31 patients with axial involvement alone), 30 patients with rheumatoid arthritis (RA) and 30 healthy volunteers using flow cytometry.
Localization (proportions) of CD19 in joint
3) Confidence 0.62 Published 2009 Journal Chin. Med. J. Section Body Doc Link 19781326 Disease Relevance 0.19 Pain Relevance 0
METHODS: We detected the proportions of CD19(+) B-cell, naive B-cell (CD19(+)CD27-), memory B-cell (CD19(+)CD27dim) and plasmablast (CD19(+)CD27high) in peripheral blood of 66 patients with AS (39 at active stage, 27 at stable stage; 35 patients with peripheral joint involvement, 31 patients with axial involvement alone), 30 patients with rheumatoid arthritis (RA) and 30 healthy volunteers using flow cytometry.
Localization (proportions) of CD19 in joint
4) Confidence 0.62 Published 2009 Journal Chin. Med. J. Section Body Doc Link 19781326 Disease Relevance 0.19 Pain Relevance 0
Flow cytometric analysis showed that CD45 positive NA-BMCs were positive for CD11b, CD90 and had low amounts of CD4+, CD8+, CD19+, and CD117+ cells.
Localization (amounts) of CD19
5) Confidence 0.48 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701999 Disease Relevance 0.25 Pain Relevance 0.03
In order to obtain purified spleen cell populations for the real-time RT-PCR experiments, after erythrocyte lysis, the splenocytes were appropriately stained with PE anti CD11b for the mieloyd line, PE-anti-CD3 antibody for T lymphocytes and FITC anti CD19 for B lymphocytes (Miltenyi Biotec, Bologna, Italy) and the CD11b+, CD3+ CD19+ populations were purified (purity ?
Localization (populations) of CD19 in B lymphocytes
6) Confidence 0.47 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2584092 Disease Relevance 0 Pain Relevance 0.05
At four days post-transduction, B cells expressing M2 were CD19+, CD25high, GL7high, B220low, I-Ab low, surface IgD?
Localization (were) of CD19 in B cells
7) Confidence 0.45 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2270344 Disease Relevance 0.15 Pain Relevance 0
Phycoerythrin (PE)-conjugated mAbs (mouse IgG1) directed against CD4, CD8, CD19, CD 14, CD55, CD68, and Cy-conjugated mAbs (mouse IgG1) against CD25 were used.
Localization (directed) of CD19
8) Confidence 0.22 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628152 Disease Relevance 0 Pain Relevance 0

General Comments

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