INT163201

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Context Info
Confidence 0.65
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.07
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (Gnpda1) carbohydrate metabolic process (Gnpda1) cytoplasm (Gnpda1)
Anatomy Link Frequency
pore 1
Gnpda1 (Mus musculus)
Pain Link Frequency Relevance Heat
IPN 6 96.84 Very High Very High Very High
rheumatoid arthritis 50 89.60 High High
Inflammation 12 88.20 High High
Arthritis 10 84.96 Quite High
cytokine 4 49.28 Quite Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 17 98.68 Very High Very High Very High
Synovitis 4 93.48 High High
Rheumatoid Arthritis 50 89.60 High High
Arthritis 12 88.20 High High
Arthropathy 4 75.92 Quite High
Severe Combined Immunodeficiency 1 58.84 Quite High
INFLAMMATION 13 35.60 Quite Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Immunization 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A pathogenic role for IgG autoantibodies to glucose-6-phosphate isomerase (GPI) has been documented in the KRN/NOD model; it was found that infusions of these autoantibodies into otherwise healthy mice rapidly led to the development of synovitis [14].
Gene_expression (autoantibodies) of glucose-6-phosphate isomerase associated with synovitis
1) Confidence 0.65 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC2833442 Disease Relevance 1.07 Pain Relevance 0.23
This is because the presence of GNP-PDMA can improve the compatibility of GNPs with the whole sequencing system, enhance the entanglement degree of networks, and increase the GNP concentration in system, which consequently lead to higher restriction and stability, higher apparent molecular weight (MW), and smaller pore size of the total sieving networks.
Gene_expression (presence) of GNP-PDMA in pore
2) Confidence 0.06 Published 2009 Journal Talanta Section Abstract Doc Link 19782213 Disease Relevance 0 Pain Relevance 0.52

General Comments

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