INT163216

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Context Info
Confidence 0.42
First Reported 2003
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Sstr2) plasma membrane (Sstr2) cytoplasm (Sstr2)
signal transducer activity (Sstr2)
Anatomy Link Frequency
neurons 2
Sstr2 (Mus musculus)
Pain Link Frequency Relevance Heat
substantia gelatinosa 9 99.68 Very High Very High Very High
agonist 5 96.00 Very High Very High Very High
Somatostatin 57 95.04 Very High Very High Very High
Spinal cord 2 87.36 High High
Pain 1 86.16 High High
primary afferent fibers 1 77.60 Quite High
unmyelinated 1 76.56 Quite High
Adelta 1 75.64 Quite High
Substantia gelatinosa neuron 1 75.00 Quite High
nMDA receptor antagonist 1 63.52 Quite High
Disease Link Frequency Relevance Heat
Pain 1 86.16 High High
Nociception 1 79.88 Quite High
Cancer 1 5.00 Very Low Very Low Very Low
Facial Pain 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, SSTR2 mRNA expression was detected on the SG neurons using single cell RT-PCR in juvenile mice.
Regulation (detected) of Transcription (expression) of SSTR2 in neurons associated with substantia gelatinosa
1) Confidence 0.42 Published 2009 Journal Brain Res. Section Abstract Doc Link 19782664 Disease Relevance 0.17 Pain Relevance 1.27
To approach a possible transcriptional regulation of sst2 receptor expression by testosterone, sst2 mRNAs were measured by semi-quantitative RT-PCR in the extracts obtained from cells cultured in the presence or in the absence of testosterone.
Spec (possible) Regulation (regulation) of Spec (possible) Transcription (transcriptional) of sst2
2) Confidence 0.05 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC151791 Disease Relevance 0 Pain Relevance 0.21

General Comments

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