INT163240

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Context Info
Confidence 0.78
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.16
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grik2) plasma membrane (Grik2)
Anatomy Link Frequency
visceral 1
spinal cord 1
anterior pituitary 1
Grik2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 1 100.00 Very High Very High Very High
Glutamate 12 97.66 Very High Very High Very High
Neurotransmitter 8 91.16 High High
Peripheral nervous system 1 68.48 Quite High
gABA 15 68.00 Quite High
IPN 4 50.00 Quite Low
intrathecal 2 50.00 Quite Low
Pain 6 10.00 Low Low
Analgesic 4 10.00 Low Low
antagonist 39 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 4 85.32 High High
Adenoma 5 39.24 Quite Low
Attention Deficit Hyperactivity Disorder 1 15.44 Low Low
Sprains And Strains 1 10.76 Low Low
Stress 48 5.00 Very Low Very Low Very Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low
Cancer 22 5.00 Very Low Very Low Very Low
Targeted Disruption 22 5.00 Very Low Very Low Very Low
Pituitary Cancer 11 5.00 Very Low Very Low Very Low
Starvation 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: The expression of GluR6 in the spinal cord of rats increased after the formalin injection.
Gene_expression (expression) of GluR6 in spinal cord
1) Confidence 0.78 Published 2009 Journal Neurosci Bull Section Body Doc Link 19784088 Disease Relevance 0.09 Pain Relevance 0
Moreover, pre-treatment of GluR6 antisense ODNs could suppress GluR6 expression in the spinal cord of rats and decrease the scores of visceral pain at 45 min following formalin injection.
Gene_expression (expression) of GluR6 in visceral
2) Confidence 0.78 Published 2009 Journal Neurosci Bull Section Body Doc Link 19784088 Disease Relevance 0.08 Pain Relevance 0
Glutamate or certain aspartate analogues have been found to stimulate PRL, GH and LH release and rat anterior pituitary cells express mRNA of glutamate receptors GluR1, GluR2, GluR3, GluR4, GluR5, GluR6, GluR7, KA1 and KA2 subunits (765).
Gene_expression (express) of GluR6 in anterior pituitary associated with glutamate and glutamate receptor
3) Confidence 0.15 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0 Pain Relevance 0.64

General Comments

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