INT163301

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.95
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
Anatomy Link Frequency
monocyte 1
IFNA1 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 31 92.60 High High
Inflammatory response 1 89.60 High High
Inflammation 8 89.20 High High
cINOD 1 85.36 High High
Arthritis 4 73.16 Quite High
chemokine 55 50.00 Quite Low
cerebral cortex 1 21.60 Low Low
Hippocampus 1 20.80 Low Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Delirium 13 100.00 Very High Very High Very High
Necrosis 2 99.70 Very High Very High Very High
Cancer 2 99.52 Very High Very High Very High
Systemic Lupus Erythematosus 35 98.96 Very High Very High Very High
Disease 7 97.24 Very High Very High Very High
Syndrome 5 91.28 High High
INFLAMMATION 10 89.20 High High
Infectious Arthritis 5 87.20 High High
Autoimmune Disease 5 79.28 Quite High
Arthritis 5 76.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors performed a prospective study using a cohort of 59 patients with SLE and compared those with and without ACS as well as associations between ACS and each CSF test [IL-6, IL-8, IFN-?
IFN Binding (associations) of IL-6 associated with delirium and systemic lupus erythematosus
1) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 1.76 Pain Relevance 0.05
Macrophages recruited by monocyte chemoattractant protein-1 (MCP-1/CCL2) and activated by interferon, and proinflammatory mediators like tumour necrosis factor alpha, interferon gamma, interleukin-6 and interleukin-1beta appear to be common elements in this group of diseases.
interferon Binding (gamma) of interleukin-6 in monocyte associated with necrosis, cancer and disease
2) Confidence 0.01 Published 2009 Journal Pharmacol. Ther. Section Abstract Doc Link 19788897 Disease Relevance 1.18 Pain Relevance 0.21

General Comments

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