INT163361

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 6.60
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SAMSN1) nucleus (SAMSN1) cytoplasm (SAMSN1)
Anatomy Link Frequency
body 1
SAMSN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 67 98.86 Very High Very High Very High
Inflammation 13 98.60 Very High Very High Very High
cINOD 2 70.20 Quite High
alcohol 27 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nash(non-alcoholic Steatohepatitis) 281 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 15 100.00 Very High Very High Very High
Body Weight 1 99.48 Very High Very High Very High
Fibrosis 67 98.86 Very High Very High Very High
INFLAMMATION 14 98.60 Very High Very High Very High
Hepatitis 63 98.48 Very High Very High Very High
Metabolic Syndrome 8 96.74 Very High Very High Very High
Insulin Resistance 14 96.34 Very High Very High Very High
Cirrhosis 15 91.76 High High
Fatty Liver 88 90.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies have identified community prevalence, clinical outcomes, association with insulin resistance, metabolic syndrome and hypoadiponectinemia, developed and explored animal models for mechanisms of inflammation and fibrosis, conceptualized etiopathogenesis, and demonstrated that NASH can be reversed by lowering body weight and increasing physical activity.
Negative_regulation (reversed) of NASH in body associated with fibrosis, nash(non-alcoholic steatohepatitis), body weight, inflammation, metabolic syndrome and insulin resistance
1) Confidence 0.42 Published 2009 Journal J. Gastroenterol. Hepatol. Section Abstract Doc Link 19799688 Disease Relevance 2.14 Pain Relevance 0.24
However the decrease of apolipoprotein A1 in NASH was much lower than in patients with ASH.
Negative_regulation (decrease) of NASH associated with nash(non-alcoholic steatohepatitis), hepatitis and disorder of lipid metabolism
2) Confidence 0.41 Published 2006 Journal BMC Gastroenterol Section Body Doc Link PMC1657015 Disease Relevance 1.90 Pain Relevance 0.03
Diagnostic values of NT for predicting borderline NASH and NASH in different groups, are given in Table 4 for the concordance with biopsy results, and in Table 5 for sensitivity, specificity and predictive values.
Negative_regulation (predicting) of NASH associated with nash(non-alcoholic steatohepatitis)
3) Confidence 0.35 Published 2006 Journal BMC Gastroenterol Section Body Doc Link PMC1657015 Disease Relevance 1.28 Pain Relevance 0.08
Diagnostic values of NT for predicting borderline NASH and NASH in different groups, are given in Table 4 for the concordance with biopsy results, and in Table 5 for sensitivity, specificity and predictive values.
Negative_regulation (predicting) of NASH associated with nash(non-alcoholic steatohepatitis)
4) Confidence 0.35 Published 2006 Journal BMC Gastroenterol Section Body Doc Link PMC1657015 Disease Relevance 1.28 Pain Relevance 0.08

General Comments

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