INT163376

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.57
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (RYBP, Casp3) cytoplasm (RYBP, Casp3) nucleus (RYBP, Casp3)
nucleoplasm (RYBP) mitochondrion (Casp3) DNA binding (RYBP)
Anatomy Link Frequency
livers 4
RYBP (Homo sapiens)
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 9 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Necrosis 2 93.56 High High
Apoptosis 2 93.04 High High
Cancer 1 85.60 High High
Hepatotoxicity 1 77.80 Quite High
Injury 2 75.00 Quite High
Toxicity 2 61.88 Quite High
Liver Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, according to the results from Western blot analysis, ASE markedly decreased APAP-induced caspase-3 and -8 protein expressions in mouse livers.
APAP Positive_regulation (induced) of Gene_expression (expressions) of caspase-3 in livers associated with paracetamol
1) Confidence 0.01 Published 2009 Journal Biol. Pharm. Bull. Section Abstract Doc Link 19801828 Disease Relevance 0.51 Pain Relevance 0.59
Furthermore, according to the results from Western blot analysis, EEP decreased APAP-induced caspase-3 and caspase-8 protein expressions in mouse livers markedly.
APAP Positive_regulation (induced) of Gene_expression (expressions) of caspase-3 in livers
2) Confidence 0.00 Published 2010 Journal J Ethnopharmacol Section Body Doc Link 19833181 Disease Relevance 0.06 Pain Relevance 0

General Comments

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