INT163396

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
sciatic nerves 2
IGKV2-30 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 5 100.00 Very High Very High Very High
metalloproteinase 1 100.00 Very High Very High Very High
Sciatic nerve 1 100.00 Very High Very High Very High
Demyelination 1 99.76 Very High Very High Very High
Inflammation 4 99.48 Very High Very High Very High
Peripheral nervous system 1 83.56 Quite High
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 5 100.00 Very High Very High Very High
Demyelinating Disease 3 99.76 Very High Very High Very High
INFLAMMATION 4 99.48 Very High Very High Very High
Immunization 1 96.60 Very High Very High Very High
Paraparesis 1 94.76 High High
Polyradiculoneuropathy 1 86.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
T cell, B cell, and macrophage infiltration, inflammatory demyelination, and local expression of interleukine-17 and matrix metalloproteinase-9 in sciatic nerves of EAN rats were significantly decreased by AUY954 treatment.
Negative_regulation (decreased) of Gene_expression (expression) of interleukine-17 in sciatic nerves associated with demyelination, inflammation, metalloproteinase, sciatic nerve and neuritis
1) Confidence 0.00 Published 2009 Journal J. Neuroimmunol. Section Abstract Doc Link 19804913 Disease Relevance 1.24 Pain Relevance 0.80

General Comments

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