INT163403

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Context Info
Confidence 0.52
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA, MMP2) extracellular region (VEGFA, MMP2) proteinaceous extracellular matrix (VEGFA, MMP2)
cytoplasm (VEGFA) peptidase activity (MMP2) growth (VEGFA)
VEGFA (Homo sapiens)
MMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 100.00 Very High Very High Very High
Analgesic 2 65.72 Quite High
Disease Link Frequency Relevance Heat
Cancer 2 67.08 Quite High
Immunotherapy Of Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both C. yanhusuo extract and its active compound berberine significantly suppressed the VEGF-induced upregulation of matrix metalloproteinase 2 (MMP2) at both mRNA and protein levels.
VEGF Positive_regulation (upregulation) of matrix metalloproteinase 2 associated with metalloproteinase
1) Confidence 0.52 Published 2009 Journal Oncol. Res. Section Abstract Doc Link 19806782 Disease Relevance 0.07 Pain Relevance 0.12
Both C. yanhusuo extract and its active compound berberine significantly suppressed the VEGF-induced upregulation of matrix metalloproteinase 2 (MMP2) at both mRNA and protein levels.
VEGF Positive_regulation (upregulation) of MMP2 associated with metalloproteinase
2) Confidence 0.52 Published 2009 Journal Oncol. Res. Section Abstract Doc Link 19806782 Disease Relevance 0.07 Pain Relevance 0.12

General Comments

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