INT163408

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.56
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Crhr2) endoplasmic reticulum (Crhr2) plasma membrane (Crhr2)
signal transducer activity (Crhr2)
Crhr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spastic colon 2 75.00 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

9 99.76 Very High Very High Very High
Stress 10 99.64 Very High Very High Very High
Sprains And Strains 2 85.04 High High
Functional Bowel Disorder 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, distal CRFR1 and CRFR2 levels were higher in MS rats but were significantly reduced post OF stress.
Negative_regulation (reduced) of Gene_expression (levels) of CRFR2 associated with stress
1) Confidence 0.27 Published 2010 Journal Peptides Section Abstract Doc Link 20096320 Disease Relevance 0.29 Pain Relevance 0.07
CRD stimulated decreased expression of CRFR2 in WKY rats alone.
Negative_regulation (decreased) of Gene_expression (expression) of CRFR2
2) Confidence 0.23 Published 2010 Journal Neurogastroenterol. Motil. Section Abstract Doc Link 19807869 Disease Relevance 0.50 Pain Relevance 0.05

General Comments

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