INT163411

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.94 Pain Relevance 0.05

Golgi apparatus (Crhr2) endoplasmic reticulum (Crhr2) plasma membrane (Crhr2) nucleus (CRX) signal transducer activity (Crhr2)

CRX (Homo sapiens) Crhr2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat spastic colon 1 53.20 Pain 1 25.00

Disease Link Frequency Relevance Heat Irritable Bowel Syndrome / Irritable Bowel Syndrome Super 5 100.00 Stress 6 93.12 Sprains And Strains 2 85.64 Functional Bowel Disorder 1 53.20

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CRD stimulated decreased expression of CRFR2 in WKY rats alone.

CRD Negative_regulation (decreased) of Gene_expression (expression) of CRFR2

1) Confidence 0.02 Published 2010 Journal Neurogastroenterol. Motil. Section Abstract Doc Link 19807869 Disease Relevance 0.50 Pain Relevance 0.05

General Comments

This test has worked.