INT163416

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.52
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Sub1) nucleus (Sub1) DNA binding (Sub1)
Anatomy Link Frequency
testis 1
smooth muscle 1
cleavage 1
Sub1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 2 98.76 Very High Very High Very High
Chronic pancreatitis 1 69.84 Quite High
adenocard 3 33.44 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 2 98.76 Very High Very High Very High
Testicular Cancer 21 86.24 High High
Pancreatitis 1 69.84 Quite High
Cancer 6 68.24 Quite High
Germ Cell And Embryonal Neoplasms 3 66.20 Quite High
Targeted Disruption 1 65.24 Quite High
Repression 6 43.20 Quite Low
Reprotox - General 3 6 5.00 Very Low Very Low Very Low
Neurological Disease 3 5.00 Very Low Very Low Very Low
Seminoma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
end adenylation or uridylation could be distinguished from differential cleavage site selection, we found a relative increase in this modification from P7 to P14.
Positive_regulation (increase) of P14 in cleavage
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012074 Disease Relevance 0 Pain Relevance 0
The increase in uridylation at P14, decreasing target specificity and miRNA stability, argue for a relatively lower effectiveness of these miRNAs against target at this time.
Positive_regulation (increase) of P14
2) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012074 Disease Relevance 0 Pain Relevance 0
This correlates with the dramatic increase in overall miRNAs at postnatal day 14 (P14) when pachytene cells are first abundant in the testis.
Positive_regulation (increase) of P14 in testis
3) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012074 Disease Relevance 0.29 Pain Relevance 0
After induction of pancreatic fibrosis, BM-derived cells accounted for 20.2% of alpha-smooth muscle actin-positive activated PSCs.
Positive_regulation (activated) of actin-positive in smooth muscle associated with fibrosis
4) Confidence 0.06 Published 2009 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 19808658 Disease Relevance 0.23 Pain Relevance 0.12

General Comments

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