INT163441

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.16
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fgb) extracellular space (Fgb) extracellular region (Fgb)
protein binding, bridging (Fgb)
Anatomy Link Frequency
blood 1
Fgb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 8 94.52 High High
Inflammation 2 89.84 High High
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 5 99.32 Very High Very High Very High
Coronary Artery Disease 26 98.56 Very High Very High Very High
Cv General 3 Under Development 8 94.52 High High
Syndrome 7 93.36 High High
INFLAMMATION 3 89.84 High High
Metabolic Disorder 1 88.60 High High
Acute Coronary Syndrome 8 83.76 Quite High
Pathologic Constriction 3 82.68 Quite High
Disease 20 73.76 Quite High
Myocardial Infarction 15 41.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, homozygotes for the minor alleles of rs1800787 and rs1800789 SNPs in FGB gene exhibited a decreased risk of CAD remaining statistically significant after adjustment for confounding factors.
Localization (alleles) of FGB associated with coronary artery disease
1) Confidence 0.50 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2834581 Disease Relevance 0.77 Pain Relevance 0
In conclusion, fibrinogen beta chain, fibrinogen gamma chain, alpha1-antitrypsin, transthyretinc, haptoglobin beta chain, ApoA-IV, ApoA-I and haptoglobin alpha2 chain are differentially expressed in the patients with unstable angina blood-stasis syndrome and control group, some differentially expressed proteins were correlated with inflammatory reaction or lipid metabolic disorder, and these proteins could provide clues to the study and discovery of new protein targets for antianginal drugs.
Localization (alpha1-antitrypsin) of fibrinogen beta chain in blood associated with metabolic disorder, angina, inflammation and syndrome
2) Confidence 0.02 Published 2009 Journal Guang Pu Xue Yu Guang Pu Fen Xi Section Abstract Doc Link 19810551 Disease Relevance 1.39 Pain Relevance 0.60

General Comments

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