INT163462

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ABL1) protein modification process (ABL1) mitochondrion (ABL1)
nucleolus (ABL1) nucleus (ABL1) DNA binding (ABL1)
ABL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 59.60 Quite High
Disease Link Frequency Relevance Heat
Disease 3 98.00 Very High Very High Very High
Gastrointestinal Stromal Tumor 6 95.28 Very High Very High Very High
Myeloid Leukemia 4 93.16 High High
Leukemia 2 92.96 High High
Arthralgia 1 60.08 Quite High
Cramps 1 59.12 Quite High
Pressure And Volume Under Development 1 57.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The introduction of imatinib, a tyrosine kinase inhibitor mainly targeting BCR-ABL, c-KIT and PDGFR, has profoundly improved the prognosis of both entities, while being surprisingly well tolerated.
Negative_regulation (inhibitor) of Regulation (targeting) of BCR-ABL
1) Confidence 0.11 Published 2009 Journal Drug Saf Section Abstract Doc Link 19810774 Disease Relevance 1.17 Pain Relevance 0.06

General Comments

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