INT163508

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2009
Negated 2
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.65
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Akt1) transport (Akt1) aging (Akt1)
enzyme binding (Akt1) carbohydrate metabolic process (Akt1) cytoplasm (Akt1)
Akt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 6 99.52 Very High Very High Very High
depression 8 97.76 Very High Very High Very High
antidepressant 10 92.56 High High
fluoxetine 2 73.40 Quite High
Eae 2 66.24 Quite High
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 8 97.76 Very High Very High Very High
Urological Neuroanatomy 10 96.48 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 2 95.44 Very High Very High Very High
Stress 15 93.52 High High
Diabetes Mellitus 39 50.00 Quite Low
Hyperglycemia 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Renal Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, levels of Akt and phospho-Akt in all experimental groups remained unchanged.
Neg (unchanged) Regulation (unchanged) of Gene_expression (levels) of Akt
1) Confidence 0.45 Published 2009 Journal Pharmacol Rep Section Abstract Doc Link 19815943 Disease Relevance 0.82 Pain Relevance 0.46
Moreover, levels of Akt and phospho-Akt in all experimental groups remained unchanged.
Neg (unchanged) Regulation (unchanged) of Gene_expression (levels) of Akt
2) Confidence 0.45 Published 2009 Journal Pharmacol Rep Section Abstract Doc Link 19815943 Disease Relevance 0.82 Pain Relevance 0.46
To confirm the validity of these data obtained in the MCT immortalized cells, we studied the effects of high glucose on the phosphorylation of Akt and tuberin and on OGG1 protein expression in RPTE cells.
Regulation (effects) of Gene_expression (expression) of Akt
3) Confidence 0.37 Published 2008 Journal Diabetes Section Body Doc Link PMC2551671 Disease Relevance 0 Pain Relevance 0

General Comments

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