INT163514

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.21
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ngf, Calca) extracellular region (Ngf, Calca) signal transduction (Ngf)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
nerve 4
Ngf (Mus musculus)
Calca (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 20 100.00 Very High Very High Very High
Calcitonin gene-related peptide 4 100.00 Very High Very High Very High
substance P 2 100.00 Very High Very High Very High
allodynia 12 97.84 Very High Very High Very High
diabetic neuropathy 2 94.76 High High
dorsal root ganglion 10 84.72 Quite High
Pain 4 25.00 Low Low
Painful diabetic neuropathy 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 4 100.00 Very High Very High Very High
Diabetes Mellitus 4 99.08 Very High Very High Very High
Neuropathic Pain 14 97.84 Very High Very High Very High
Diabetic Neuropathy 4 94.76 High High
Ganglion Cysts 10 83.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesized that nerve growth factor (NGF), which enhances the expression of key mediators of nociception (i.e. substance P [SP] and calcitonin gene-related peptide), contributes to the development of mechanical allodynia in these mice.
nerve growth factor Positive_regulation (enhances) of Gene_expression (expression) of calcitonin in nerve associated with nociception, allodynia, nerve growth factor, calcitonin gene-related peptide and substance p
1) Confidence 0.30 Published 2009 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 19816194 Disease Relevance 1.11 Pain Relevance 0.91
We hypothesized that nerve growth factor (NGF), which enhances the expression of key mediators of nociception (i.e. substance P [SP] and calcitonin gene-related peptide), contributes to the development of mechanical allodynia in these mice.
NGF Positive_regulation (enhances) of Gene_expression (expression) of calcitonin in nerve associated with nociception, allodynia, nerve growth factor, calcitonin gene-related peptide and substance p
2) Confidence 0.30 Published 2009 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 19816194 Disease Relevance 1.11 Pain Relevance 0.91

General Comments

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