INT163562

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (MN1) cellular_component (MN1) biological_process (MN1)
MN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 98.08 Very High Very High Very High
rheumatoid arthritis 6 88.88 High High
spinal inflammation 6 88.40 High High
Rheumatism 1 45.16 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 98.08 Very High Very High Very High
Rheumatoid Arthritis 6 85.68 High High
Low Back Pain 6 75.00 Quite High
Disease 3 57.04 Quite High
Rheumatic Diseases 1 45.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several different mechanisms may mediate this phenomenon; among them are alterations in number, binding affinity or phosphorylation status of the GCR, polymorphic changes and/or over-expression of chaperones/ co-chaperones, increased expression of inflammatory transcription factors, the multidrug resistance pump, over-expression of the GCR beta isoform, alteration in the expression of mGCR and imbalance of 11beta-hydroxysteroid dehydrogenase type 1 & 2 activity.
Regulation (alteration) of Gene_expression (expression) of mGCR associated with inflammation
1) Confidence 0.07 Published 2009 Journal Clin. Exp. Rheumatol. Section Abstract Doc Link 19822064 Disease Relevance 0.76 Pain Relevance 0.64

General Comments

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