INT16358

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Context Info
Confidence 0.41
First Reported 1991
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NPPA) nucleus (NPPA) cytoplasm (NPPA)
Anatomy Link Frequency
plasma 2
NPPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 93.40 High High
Paresthesia 1 92.08 High High
cva 1 48.88 Quite Low
Disease Link Frequency Relevance Heat
Natriuresis 3 100.00 Very High Very High Very High
Body Weight 1 100.00 Very High Very High Very High
Arthralgia 1 93.40 High High
Pressure And Volume Under Development 6 90.96 High High
Hemorrhage 1 48.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, 14 days of high dose GH administration caused a significant increase in ECV and a significant suppression of ANP.
Positive_regulation (caused) of Negative_regulation (suppression) of ANP
1) Confidence 0.41 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1826008 Disease Relevance 0.40 Pain Relevance 0.14
Spironolactone induced a significant reduction of plasma volume (42.1 +/- 5.5 to 36.1 +/- 6.6 mL/kg body weight, P < .01) and of the concentration of alpha-atrial natriuretic peptide (alpha-ANP) (39.8 +/- 22 to 27.7 +/- 20 pg/mL, P < .01); in addition, a pronounced increase in plasma renin activity (PRA) (1.1 +/- 0.9 to 7.5 +/- 3.4 ng/mL/h, P < .001) was induced by the treatment.
Positive_regulation (induced) of Negative_regulation (reduction) of natriuretic peptide in plasma associated with natriuresis and body weight
2) Confidence 0.07 Published 1996 Journal Hepatology Section Abstract Doc Link 8621132 Disease Relevance 0.43 Pain Relevance 0.07

General Comments

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