INT163580

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.85
Pain Relevance 2.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Fst) nucleus (Fst) cytoplasm (Fst)
Fst (Mus musculus)
Pain Link Frequency Relevance Heat
Endocannabinoid 95 100.00 Very High Very High Very High
Eae 19 100.00 Very High Very High Very High
agonist 15 100.00 Very High Very High Very High
Inflammatory response 11 99.96 Very High Very High Very High
Dopamine 4 99.68 Very High Very High Very High
Serotonin 13 99.42 Very High Very High Very High
Neurotransmitter 9 99.20 Very High Very High Very High
antidepressant 30 98.40 Very High Very High Very High
Central nervous system 25 95.80 Very High Very High Very High
monoamine 4 95.64 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 93 99.96 Very High Very High Very High
Gliosis 23 98.20 Very High Very High Very High
Neurodegenerative Disease 134 97.44 Very High Very High Very High
Sprains And Strains 1 91.84 High High
Depression 24 89.24 High High
Anxiety Disorder 109 83.52 Quite High
Targeted Disruption 109 82.04 Quite High
Stress 37 77.44 Quite High
Disease 7 54.80 Quite High
Frailty 2 52.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, serotonin and dopamine concentrations increased after FST, but no changes in neurotransmitter concentrations were observed after TS [40].
Positive_regulation (increased) of FST associated with neurotransmitter, dopamine, eae and serotonin
1) Confidence 0.19 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565062 Disease Relevance 0.47 Pain Relevance 0.80
This (FS-288)-induced inflammatory response, in turn, led to a profound reduction in neurogenesis, an effect that was reversed by the administration of NSAIDs.
Positive_regulation (induced) of FS-288 associated with inflammatory response, cinod and neurodegenerative disease
2) Confidence 0.10 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 1.51 Pain Relevance 0.75
RESULTS: While leptin and fluoxetine showed similar antidepressant-like behavioral effects in the TST and FST, they differed in the behavioral assays for anxiety.
Positive_regulation (effects) of FST
3) Confidence 0.09 Published 2010 Journal Psychopharmacology (Berl.) Section Body Doc Link 19823809 Disease Relevance 0.14 Pain Relevance 0
In the rat FST, administration of AM404 (endocannabinoid uptake inhibitor) and HU-210, a potent CB1 receptor agonist, induced decreases in immobility (indicative of antidepressant activity) that were blocked by pretreatment with the selective CB1 receptor antagonist AM251.
Positive_regulation (induced) of FST associated with endocannabinoid, antidepressant, antagonist and agonist
4) Confidence 0.09 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1906867 Disease Relevance 0.72 Pain Relevance 0.62

General Comments

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