INT163585

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.14 Pain Relevance 0

cytosol (Epm2a) signal transduction (Lep) extracellular space (Lep) extracellular region (Lep) nucleus (Epm2a) intracellular (Lep)

Anatomy Link Frequency arm 2 Lep (Mus musculus) Epm2a (Mus musculus)

Pain Link Frequency Relevance Heat fluoxetine 1 50.00 sSRI 3 5.00 antidepressant 2 5.00

Disease Link Frequency Relevance Heat Anxiety Disorder 3 68.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Open arm exploration in the EPM was increased by leptin but decreased by fluoxetine.

leptin Positive_regulation (increased) of Gene_expression (exploration) of EPM in arm

1) Confidence 0.03 Published 2010 Journal Psychopharmacology (Berl.) Section Body Doc Link 19823809 Disease Relevance 0.14 Pain Relevance 0

General Comments

This test has worked.