INT163599

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.15
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ciita)
Anatomy Link Frequency
macrophages 1
Ciita (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 18 99.10 Very High Very High Very High
Inflammation 2 81.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 81.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In agreement with this, treatment of the cells with capsaicin also inhibited MHC class II transactivator (CIITA) mRNA expression induced by IFN-gamma in a dose-dependent manner.
Transcription (expression) of CIITA associated with qutenza
1) Confidence 0.49 Published 2010 Journal Int. Immunopharmacol. Section Abstract Doc Link 19825429 Disease Relevance 0.08 Pain Relevance 0.69
These findings suggest that capsaicin suppresses expression of MHC class II via downregulation of CIITA transcription but not through the mediation of nitric oxide production by macrophages.
Transcription (transcription) of CIITA in macrophages associated with qutenza
2) Confidence 0.49 Published 2010 Journal Int. Immunopharmacol. Section Abstract Doc Link 19825429 Disease Relevance 0.07 Pain Relevance 0.68

General Comments

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