INT16364
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
RESULTS: Immunohistochemical analysis revealed significantly increased expression of HLA-DR antigen in the glandular cells in eutopic and ectopic endometria, compared with materials from patients with adenomyoma and infertile patients. | |||||||||||||||
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OBJECTIVE: To evaluate the expression of major histocompatibility complex class II antigen (human leukocyte antigen, HLA-DR) in glandular cells in eutopic and ectopic endometria in patients with endometriosis and adenomyosis. | |||||||||||||||
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DESIGN: Glandular cells in eutopic and ectopic endometria were analyzed immunohistochemically to localize the expression of HLA-DR antigen. | |||||||||||||||
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CONCLUSIONS: It is likely that aberrant expression of HLA-DR antigen in glandular cells of eutopic and ectopic endometria in endometriosis and adenomyosis is deeply involved in various immunological abnormalities.
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Experimental and clinical significance of endotoxin-dependent HLA-DR expression on monocytes. | |||||||||||||||
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LPS, added experimentally to whole blood, enhanced HLA-DR expression on monocytes without further manipulation. | |||||||||||||||
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Different HLA-DR expression in endometriotic and adenomyotic lesions: correlation with transvaginal ultrasonography findings. | |||||||||||||||
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CONCLUSION: HLA-DR antigen expression in endometrium and adenomyotic tissues. | |||||||||||||||
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In both groups the HLA-DR expression was significantly higher in the secretory phase than the proliferative or glandular and stroma cells. | |||||||||||||||
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We investigated the expression of HLA-DR in endometriotic and adenomyotic tissues within the stromal and glandular cells. | |||||||||||||||
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Moreover, we correlate the HLA-DR expression according the transvaginal ultrasonography findings. | |||||||||||||||
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However, HLA-DR expression is distributed preferentially in glandular epithelial cells in endometrioma and in the adenomyotic stroma. | |||||||||||||||
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The significance of de novo expression of HLA-DR antigen by duct cells is discussed. | |||||||||||||||
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In chronic obstructive pancreatitis, the duct cells strongly expressed the HLA-DR antigen. | |||||||||||||||
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Lymphocyte subsets and HLA-DR expression in normal pancreas and chronic pancreatitis. | |||||||||||||||
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This study was prospectively carried out in order to clarify if an aberrant expression of HLA-DR molecules could take part in the pathogenesis of chronic pancreatitis. | |||||||||||||||
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Strong HLA-DR expression was observed in 6/12 chronic pancreatitis patients and in 1/9 controls. | |||||||||||||||
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RESULTS: In adenomyosis tissues, the percentage of HLA-DR cells expression was significantly higher in stromal cells (83.9%) compared to glandular cells (25.8%), (p<0.001). | |||||||||||||||
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These results suggest that significant changes in insulin and glucagon production occur in the transplanted pancreas with rejection and that HLA-DR is not expressed by islet cells during graft rejection or with chronic inflammation. | |||||||||||||||
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Pancreas transplantation: an immunohistochemical analysis of pancreatic hormones and HLA-DR expression. | |||||||||||||||
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