INT163675

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Context Info
Confidence 0.13
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnr) extracellular region (Tnr) nucleolus (Tnr)
proteinaceous extracellular matrix (Tnr) nucleus (Tnr) extracellular matrix organization (Tnr)
Anatomy Link Frequency
liver 1
Schwann cells 1
Tnr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
neuralgia 2 50.00 Quite Low
cryotherapy 6 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
fifth nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 122 100.00 Very High Very High Very High
Metastasis 50 99.68 Very High Very High Very High
Colon Cancer 32 99.34 Very High Very High Very High
Liver Cancer 28 87.84 High High
Neuralgia 2 50.00 Quite Low
Increased Venous Pressure Under Development 6 35.68 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Radiation Pneumonitis 4 5.00 Very Low Very Low Very Low
Appetite Loss 4 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: The pathological changes affect not only the central nerve fibers of the TNR, but also some of the peripheral axons, their myelin sheath and Schwann cells.
Regulation (affect) of TNR in Schwann cells
1) Confidence 0.13 Published 2009 Journal Clin Neurol Neurosurg Section Body Doc Link 19836877 Disease Relevance 0 Pain Relevance 0
With the doses used there is no correlation between MAA uptake into CRC liver metastases prior to SIRT (TNR) and response to the treatment in terms of tumour marker data, CT data or survival time.
Regulation (response) of TNR in liver associated with cancer, colon cancer and metastasis
2) Confidence 0.04 Published 2005 Journal BMC Nucl Med Section Body Doc Link PMC1360059 Disease Relevance 0.88 Pain Relevance 0
There was no correlation between TNR and tumour response based on CEA changes (r2 = 0.004).
Regulation (response) of TNR associated with cancer
3) Confidence 0.02 Published 2005 Journal BMC Nucl Med Section Abstract Doc Link PMC1360059 Disease Relevance 0.76 Pain Relevance 0

General Comments

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