INT16368

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Context Info
Confidence 0.72
First Reported 1991
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.18
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1) extracellular region (Edn1) cell-cell signaling (Edn1)
cytoplasm (Edn1)
Anatomy Link Frequency
plasma 2
Edn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Visceral pain 1 93.40 High High
Antinociceptive 1 90.00 High High
Paracetamol 1 84.24 Quite High
Morphine 5 83.56 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

1 93.40 High High
Nociception 1 82.16 Quite High
Myocardial Infarction 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: We measured plasma levels of ET-1, C-terminal degradation products of ET-1, and neutral endopeptidase 24.11 (NEP) in 68 patients with acute Q-wave myocardial infarction and 29 control subjects.
Protein_catabolism (degradation) of ET-1 in plasma
1) Confidence 0.72 Published 2001 Journal Ann Emerg Med Section Body Doc Link 11326179 Disease Relevance 0 Pain Relevance 0
The effect of big-ET-1[1-38], but not ET-1, was blocked by pretreatment with the enzyme inhibitor phosphoramidon (10 mg/kg, s.c., 30 min prior), implying that the big-ET-1[1-38] must first be enzymatically cleaved, presumably to ET-1, in order to elicit the abdominal constriction response.
Protein_catabolism (cleaved) of big-ET-1
2) Confidence 0.57 Published 1991 Journal Life Sci. Section Abstract Doc Link 1826753 Disease Relevance 0.08 Pain Relevance 0.31
METHODS: We measured plasma levels of ET-1, C-terminal degradation products of ET-1, and neutral endopeptidase 24.11 (NEP) in 68 patients with acute Q-wave myocardial infarction and 29 control subjects.
Protein_catabolism (degradation) of ET-1 in plasma
3) Confidence 0.54 Published 2001 Journal Ann Emerg Med Section Body Doc Link 11326179 Disease Relevance 0 Pain Relevance 0

General Comments

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