INT163716

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

COMMD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Buprenorphine 12 100.00 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of the UGT2B7 promoter (G-842A) mutation resulted in higher BUP glucuronidation V(max) in pooled HLMs (+80% on average) and in a significant higher glucuronidation rate in noncarriers (but not in carriers) of the UGT1A1*28 allele (P = 0.0352).
Positive_regulation (resulted) of BUP associated with buprenorphine
1) Confidence 0.32 Published 2010 Journal Drug Metab. Dispos. Section Abstract Doc Link 19841060 Disease Relevance 0 Pain Relevance 0.89

General Comments

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