INT163762

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (MDM2, BAX) cytosol (MDM2, BAX) nucleus (MDM2, BAX)
nucleoplasm (MDM2) mitochondrion (BAX) endoplasmic reticulum (BAX)
Anatomy Link Frequency
null cells 2
MDM2 (Homo sapiens)
BAX (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 5 91.32 High High
Disease Link Frequency Relevance Heat
Apoptosis 7 94.80 High High
Targeted Disruption 1 89.92 High High
Colon Cancer 2 88.08 High High
Death 1 66.40 Quite High
Immunotherapy Of Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased NO production after treatment uniformly stimulated p53 and Bax expression through Mdm2 down-regulation in p53-WT cells, whereas all were unaffected in p53-null cells.
Mdm2 Neg (NO) Positive_regulation (stimulated) of Gene_expression (expression) of Bax in null cells
1) Confidence 0.27 Published 2009 Journal Anticancer Res. Section Abstract Doc Link 19846903 Disease Relevance 0.86 Pain Relevance 0.30

General Comments

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