INT163829

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cdkn1b) endosome (Cdkn1b) cell death (Cdkn1b)
nucleus (Cdkn1b) cell cycle (Cdkn1b) protein complex (Cdkn1b)
Anatomy Link Frequency
cleavage 2
nucleus 2
Cdkn1b (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 7 99.12 Very High Very High Very High
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 7 97.68 Very High Very High Very High
Apoptosis 11 92.60 High High
Cancer 38 90.08 High High
Toxicity 1 57.60 Quite High
Glioma 26 50.00 Quite Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low
Retinoblastoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunoflourescence staining assay revealed that the treatments induced an increase in p27Kip1 localization in the nucleus when compared with control cells (Fig. 2C) and a higher number of cells expressing p27Kip1 in the nuclei was observed with the pCU treatment (Fig.
Positive_regulation (increase) of Localization (localization) of p27Kip1 in nucleus
1) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908539 Disease Relevance 0.06 Pain Relevance 0
In contrast, cell-cycle regulator p27(KIP1), caspase activity as well as poly-ADP ribose polymerase (PARP) cleavage were increased.
Positive_regulation (increased) of Localization (cleavage) of p27 in cleavage
2) Confidence 0.13 Published 2010 Journal Oncogene Section Abstract Doc Link 19855437 Disease Relevance 0.90 Pain Relevance 0.45

General Comments

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