INT163858

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.55
Pain Relevance 1.53

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mitochondrion (Cyp11a1) oxidoreductase activity (Cyp11a1) lipid metabolic process (Cyp11a1)
Cyp11a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Versed 32 97.56 Very High Very High Very High
antagonist 4 91.36 High High
Regional anesthesia 2 70.48 Quite High
Disease Link Frequency Relevance Heat
Cancer 6 82.84 Quite High
Apoptosis 4 75.00 Quite High
Death 2 62.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In both cell types, MDZ-stimulated steroidogenesis in dose- and time-dependent manners, and induced the expression of PBR and StAR proteins, but had no effect on P450scc and 3beta-HSD expressions.
Neg (no) Regulation (had) of Gene_expression (expressions) of P450scc associated with versed
1) Confidence 0.46 Published 2010 Journal Toxicol. Lett. Section Abstract Doc Link 19857560 Disease Relevance 0.28 Pain Relevance 0.76
In both cell types, MDZ-stimulated steroidogenesis in dose- and time-dependent manners, and induced the expression of PBR and StAR proteins, but had no effect on P450scc and 3beta-HSD expressions.
Neg (no) Regulation (effect) of Gene_expression (expressions) of P450scc associated with versed
2) Confidence 0.20 Published 2010 Journal Toxicol. Lett. Section Abstract Doc Link 19857560 Disease Relevance 0.28 Pain Relevance 0.76

General Comments

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