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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 1.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp11a1) oxidoreductase activity (Cyp11a1) lipid metabolic process (Cyp11a1)
Cyp11a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Versed 16 99.84 Very High Very High Very High
Paracetamol 15 99.40 Very High Very High Very High
antagonist 2 92.00 High High
Regional anesthesia 1 85.68 High High
Analgesic 1 69.36 Quite High
Disease Link Frequency Relevance Heat
Cancer 3 98.04 Very High Very High Very High
Sprains And Strains 1 86.08 High High
Body Weight 2 84.12 Quite High
Stress 1 82.16 Quite High
Nephrotoxicity 4 81.68 Quite High
Apoptosis 3 75.00 Quite High
Death 1 32.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PBR, P450scc, 3beta-HSD and StAR protein expression induced by MDZ was determined by Western blotting.
Positive_regulation (induced) of Gene_expression (expression) of P450scc associated with versed
1) Confidence 0.38 Published 2010 Journal Toxicol. Lett. Section Abstract Doc Link 19857560 Disease Relevance 0.17 Pain Relevance 0.61
Moreover, APAP administration significantly increased MDA, protein carbonylation, GSSG level, intracellular ROS production and cytochrome P450 enzyme (CYPP450) activity.
Positive_regulation (increased) of Gene_expression (production) of cytochrome P450 enzyme associated with paracetamol
2) Confidence 0.28 Published 2010 Journal Toxicology Section Abstract Doc Link 20067817 Disease Relevance 0.47 Pain Relevance 0.92

General Comments

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