INT163928

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2009
Negated 3
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 2.56
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Fabp1) mitosis (Fabp1) transport (Fabp1)
nucleus (Fabp1) cytoplasm (Fabp1)
Anatomy Link Frequency
liver 3
Fabp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 42 99.00 Very High Very High Very High
Angina 4 75.00 Quite High
Inflammation 66 63.24 Quite High
Inflammatory response 18 46.40 Quite Low
anesthesia 15 38.72 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 42 99.00 Very High Very High Very High
Acute Renal Failure 2 97.96 Very High Very High Very High
Injury 93 92.84 High High
Death 9 86.88 High High
Reperfusion Injury 3 84.68 Quite High
Renal Disease 2 81.44 Quite High
Hepatotoxicity 3 78.76 Quite High
Cirrhosis 3 77.36 Quite High
Cv General 3 Under Development 4 75.00 Quite High
INFLAMMATION 87 63.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intermittent Pringle maneuver (2 × 15 min ischemia and 5 min reperfusion) did not cause significant changes in arterial L-FABP or GST?
Neg (not) Regulation (changes) of L-FABP associated with ischemia
1) Confidence 0.34 Published 2007 Journal World J Surg Section Body Doc Link PMC2039834 Disease Relevance 0.70 Pain Relevance 0.17
Surprisingly, we found no additional effect of organ transection or intermittent Pringle maneuver on these increased L-FABP and GST?
Neg (no) Regulation (effect) of L-FABP
2) Confidence 0.34 Published 2007 Journal World J Surg Section Body Doc Link PMC2039834 Disease Relevance 0.92 Pain Relevance 0.19
Surprisingly, arterial L-FABP levels did not change significantly during subsequent intermittent Pringle maneuver, indicating that neither intermittent ischemia-reperfusion nor liver transection significantly aggravated the hepatocellular injury caused by early perioperative processes.
Neg (not) Regulation (change) of L-FABP in liver associated with ischemia and injury
3) Confidence 0.15 Published 2007 Journal World J Surg Section Body Doc Link PMC2039834 Disease Relevance 0.43 Pain Relevance 0.08
PURPOSE: The value of NGAL (neutrophil gelatinase-associated lipocalin) and L-FABP (liver-type fatty acid binding protein) has been highlighted as a novel biomarker of detection of acute renal failure in children after cardiac surgery.
Regulation (value) of L-FABP in liver associated with acute renal failure
4) Confidence 0.11 Published 2009 Journal Adv Med Sci Section Abstract Doc Link 19875355 Disease Relevance 0.25 Pain Relevance 0.14
PURPOSE: The value of NGAL (neutrophil gelatinase-associated lipocalin) and L-FABP (liver-type fatty acid binding protein) has been highlighted as a novel biomarker of detection of acute renal failure in children after cardiac surgery.
Regulation (value) of acid binding protein in liver associated with acute renal failure
5) Confidence 0.11 Published 2009 Journal Adv Med Sci Section Abstract Doc Link 19875355 Disease Relevance 0.25 Pain Relevance 0.14

General Comments

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