INT163960

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.28
Pain Relevance 1.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
hepatocytes 1
erythrocyte 1
lamina 1
Saa (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 52 99.44 Very High Very High Very High
spinal inflammation 43 97.84 Very High Very High Very High
Crohn's disease 25 90.64 High High
Inflammatory marker 8 89.96 High High
corticosteroid 1 87.04 High High
cINOD 4 84.32 Quite High
Tendonitis 2 72.48 Quite High
Arthritis 3 71.60 Quite High
cytokine 25 59.80 Quite High
ischemia 2 27.52 Quite Low
Disease Link Frequency Relevance Heat
Disease 72 100.00 Very High Very High Very High
Alzheimer's Dementia 12 100.00 Very High Very High Very High
Inflammatory Bowel Disease 21 99.72 Very High Very High Very High
Cancer 8 98.48 Very High Very High Very High
Necrosis 5 98.24 Very High Very High Very High
Low Back Pain 46 97.84 Very High Very High Very High
INFLAMMATION 61 89.64 High High
Amyloidosis 6 87.92 High High
Colitis 69 83.52 Quite High
Disorder Of Lipid Metabolism 9 78.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SAA and disease activity
Localization (disease) of SAA associated with disease
1) Confidence 0.49 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628111 Disease Relevance 1.59 Pain Relevance 1.21
chemoattractant; DCs, dendritic cells; IBD, inflammatory bowel disease; JD, Johne's disease; LP, lamina propria; MLN, mesenteric lymph nodes; pDCs, plasmacytoid dendritic cells; PP, Peyer's patches; SAA, serum amyloid A; TLR, toll-like receptor; UC, ulcerative colitis.


Localization (disease) of SAA in lamina associated with inflammatory bowel disease, inflammation, alzheimer's dementia and disease
2) Confidence 0.32 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2443107 Disease Relevance 1.33 Pain Relevance 0.17
OBJECTIVE: To study the usefulness of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and serum amyloid A (SAA) for response prediction and monitoring of anti-tumor necrosis factor (anti-TNF) treatment in ankylosing spondylitis (AS) patients.
Localization (usefulness) of SAA in erythrocyte associated with spinal inflammation, necrosis, cancer and alzheimer's dementia
3) Confidence 0.21 Published 2009 Journal Arthritis Rheum. Section Abstract Doc Link 19877087 Disease Relevance 0.69 Pain Relevance 0.17
SAA is produced by hepatocytes and secreted into the serum as well as CRP [31].
Localization (secreted) of SAA in hepatocytes
4) Confidence 0.12 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC3022197 Disease Relevance 0.67 Pain Relevance 0.20

General Comments

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