INT163962

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2010
Negated 4
Speculated 0
Reported most in Body
Documents 2
Total Number 6
Disease Relevance 3.25
Pain Relevance 2.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
peripheral nerve 2
Nav1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nav1.3 1 100.00 Very High Very High Very High
tetrodotoxin 17 99.32 Very High Very High Very High
dorsal root ganglion 182 99.12 Very High Very High Very High
nav1.8 33 96.80 Very High Very High Very High
Sciatic nerve 277 94.56 High High
Nav1.9 6 93.40 High High
sodium channel 54 90.96 High High
Pain 21 85.28 High High
Paresthesia 1 84.88 Quite High
unmyelinated 6 82.96 Quite High
Disease Link Frequency Relevance Heat
Nerve Compression Syndromes 155 99.72 Very High Very High Very High
Ganglion Cysts 182 99.12 Very High Very High Very High
Injury 201 92.68 High High
Neuropathic Pain 87 88.40 High High
Pain 11 85.28 High High
Dysesthesia 1 84.88 Quite High
Neuroma 10 69.84 Quite High
Nervous System Injury 45 41.84 Quite Low
INFLAMMATION 10 37.44 Quite Low
Nervous System Malformation 5 21.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, we were unable to observe any changes in ipsilateral mRNA levels of NaV1.3, NaV1.6, NaV1.7, or NaV1.9 (Fig. 5).
Neg (unable) Regulation (changes) of Transcription (levels) of NaV1
1) Confidence 0.35 Published 2009 Journal Mol Pain Section Body Doc Link PMC2667430 Disease Relevance 0.56 Pain Relevance 0.20
In contrast, we were unable to observe any changes in ipsilateral mRNA levels of NaV1.3, NaV1.6, NaV1.7, or NaV1.9 (Fig. 5).
Neg (unable) Regulation (changes) of Transcription (levels) of NaV1
2) Confidence 0.35 Published 2009 Journal Mol Pain Section Body Doc Link PMC2667430 Disease Relevance 0.55 Pain Relevance 0.20
In contrast, we were unable to observe any changes in ipsilateral mRNA levels of NaV1.3, NaV1.6, NaV1.7, or NaV1.9 (Fig. 5).
Neg (unable) Regulation (changes) of Transcription (levels) of NaV1
3) Confidence 0.35 Published 2009 Journal Mol Pain Section Body Doc Link PMC2667430 Disease Relevance 0.56 Pain Relevance 0.20
In contrast, we were unable to observe any changes in ipsilateral mRNA levels of NaV1.3, NaV1.6, NaV1.7, or NaV1.9 (Fig. 5).
Neg (unable) Regulation (changes) of Transcription (levels) of NaV1
4) Confidence 0.35 Published 2009 Journal Mol Pain Section Body Doc Link PMC2667430 Disease Relevance 0.56 Pain Relevance 0.20
Selectivity of peripheral nerve NaV1.8 mRNA up-regulation after SNE
Regulation (regulation) of Transcription (Selectivity) of NaV1 in peripheral nerve associated with nerve compression syndromes
5) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2667430 Disease Relevance 0.54 Pain Relevance 0.64
However, tetrodotoxin-sensitive (TTX-S) sodium-channel Nav1.3 mRNA expression remained unaltered.
Regulation (unaltered) of Transcription (expression) of Nav1 associated with nav1.3 and tetrodotoxin
6) Confidence 0.26 Published 2010 Journal J. Orthop. Res. Section Abstract Doc Link 19877286 Disease Relevance 0.49 Pain Relevance 1.19

General Comments

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