INT163963

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Rtn4) aging (Rtn4) endoplasmic reticulum (Rtn4)
plasma membrane (Rtn4) protein complex (Rtn4) cytoplasm (Rtn4)
Rtn4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nav1.8 3 100.00 Very High Very High Very High
tetrodotoxin 2 99.76 Very High Very High Very High
Nav1.9 1 98.96 Very High Very High Very High
dorsal root ganglion 2 98.24 Very High Very High Very High
sodium channel 4 97.12 Very High Very High Very High
unmyelinated 1 93.72 High High
Sciatic nerve 2 88.08 High High
nav1.3 1 84.24 Quite High
Pain 1 66.24 Quite High
Paresthesia 1 65.84 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 98.24 Very High Very High Very High
Injury 1 77.08 Quite High
Neuropathic Pain 2 69.36 Quite High
Pain 1 66.24 Quite High
Dysesthesia 1 65.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tetrodotoxin-resistant (TTX-R) sodium-channel Nav1.8 mRNA expression was significantly decreased and TTX-R sodium-channel Nav1.9 mRNA expression showed a tendency to decrease when compared with the mRNA expressions in the control groups.
Negative_regulation (decreased) of Transcription (expression) of TTX-R associated with tetrodotoxin, nav1.8 and nav1.9
1) Confidence 0.03 Published 2010 Journal J. Orthop. Res. Section Abstract Doc Link 19877286 Disease Relevance 0.45 Pain Relevance 1.06

General Comments

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