INT164070

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Context Info
Confidence 0.32
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AKT1, NFKB1) nucleus (AKT1, NFKB1) cytoplasm (AKT1, NFKB1)
cytosol (AKT1, NFKB1) signal transduction (AKT1, NFKB1) cell differentiation (AKT1)
Anatomy Link Frequency
chondrocytes 1
AKT1 (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 50.00 Quite Low
Osteoarthritis 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 89.48 High High
Apoptosis 1 50.00 Quite Low
Osteoarthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: We have recently demonstrated that in chondrocytes resveratrol modulates the NF-kappaB pathway by inhibiting the proteasome, while curcumin modulates the activation of NF-kappaB by inhibiting upstream kinases (Akt).
Akt Positive_regulation (activation) of NF-kappaB in chondrocytes
1) Confidence 0.32 Published 2009 Journal Arthritis Res. Ther. Section Body Doc Link 19889203 Disease Relevance 0.09 Pain Relevance 0

General Comments

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