INT164119

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Context Info
Confidence 0.45
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.43
Pain Relevance 0.16

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nucleus (YPEL1)
Anatomy Link Frequency
14.1 2
YPEL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 94.40 High High
Disease Link Frequency Relevance Heat
Adenocarcinoma 4 99.40 Very High Very High Very High
Pancreatic Cancer 16 99.04 Very High Very High Very High
Pancreatitis 2 94.40 High High
Malignant Neoplastic Disease 2 53.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quantitative real time polymerase chain reaction analysis revealed a significant down-regulation of YPEL1 mRNA expression in pancreatic adenocarcinoma tissues compared to normal tissues (54.1+/-5.2 vs. 85.8+/-14.1 copies/10,000 copies cpb) and low expression of this gene indicated a tendency for better survival of pancreatic cancer patients (16 vs. 13 months; p=0.17).
Regulation (regulation) of Gene_expression (expression) of YPEL1 mRNA in 14.1 associated with adenocarcinoma and pancreatic cancer
1) Confidence 0.45 Published 2009 Journal Georgian Med News Section Abstract Doc Link 19893129 Disease Relevance 0.91 Pain Relevance 0.09
Recently we have identified YPEL1 as a gene whose expression is deregulation in perineural invasive pancreatic cancer cells.
Regulation (deregulation) of Gene_expression (expression) of YPEL1 associated with pancreatic cancer
2) Confidence 0.45 Published 2009 Journal Georgian Med News Section Abstract Doc Link 19893129 Disease Relevance 0.53 Pain Relevance 0.07

General Comments

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