INT16412

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Context Info
Confidence 0.41
First Reported 1988
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.29
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nppa) nucleus (Nppa) cytoplasm (Nppa)
Nppa (Rattus norvegicus)
LH (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 7 100.00 Very High Very High Very High
opiate 1 96.48 Very High Very High Very High
Opioid 2 95.28 Very High Very High Very High
antagonist 2 94.72 High High
Dopamine 3 87.80 High High
Intracerebroventricular 1 81.52 Quite High
Disease Link Frequency Relevance Heat
Natriuresis 5 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mechanisms possibly involved in suppression of LH secretion by ANP and BNP were also examined.
ANP Negative_regulation (suppression) of Localization (secretion) of LH
1) Confidence 0.41 Published 1991 Journal Endocrinology Section Abstract Doc Link 1830270 Disease Relevance 0.21 Pain Relevance 0.38
Finally, an opiate involvement in the mechanism of ANF's action was suggested, since naloxone (0.5 mg, iv, followed by a 60-min infusion of an additional 1 mg) completely blocked the ability of ANF (0.1 or 0.5 microgram/kg.min, infused over the last 30 min of naloxone administration) to inhibit LH release.
ANF Negative_regulation (inhibit) of Localization (release) of LH associated with narcan and opiate
2) Confidence 0.26 Published 1988 Journal Endocrinology Section Abstract Doc Link 2964365 Disease Relevance 0.07 Pain Relevance 0.24

General Comments

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