INT164128

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Context Info
Confidence 0.28
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.09
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF10, MAPK14) nucleoplasm (MAPK14) response to stress (MAPK14)
cytoplasm (MAPK14) cell-cell signaling (TNFSF10) cytosol (MAPK14)
TNFSF10 (Homo sapiens)
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 50.32 Quite High
Disease Link Frequency Relevance Heat
Death 16 99.96 Very High Very High Very High
Cancer 4 75.00 Quite High
Apoptosis 4 75.00 Quite High
Necrosis 4 75.00 Quite High
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preceding cell death, TRAIL activated nuclear factor kappaB, c-Jun N-terminal kinase, p38 and p42/44.
TRAIL Positive_regulation (activated) of p38 associated with death
1) Confidence 0.28 Published 2009 Journal FEBS J. Section Abstract Doc Link 19895579 Disease Relevance 1.06 Pain Relevance 0
Although TRAIL-induced stimulation of c-Jun N-terminal kinase and p38 was caspase-dependent in a cell type-specific fashion, activation of nuclear factor kappaB and p42/44 was caspase-independent in all cases.
TRAIL Positive_regulation (stimulation) of p38
2) Confidence 0.28 Published 2009 Journal FEBS J. Section Abstract Doc Link 19895579 Disease Relevance 1.03 Pain Relevance 0.05

General Comments

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