INT164129

Context Info Confidence 0.37 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 2.04 Pain Relevance 0

nucleoplasm (MAPK9) mitochondrion (MAPK9) response to stress (MAPK9) cytoplasm (MAPK9) cell-cell signaling (TNFSF10) cytosol (MAPK9)

TNFSF10 (Homo sapiens) MAPK9 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 2 49.68

Disease Link Frequency Relevance Heat Death 16 99.96 Cancer 4 75.00 Apoptosis 4 75.00 Necrosis 4 75.00 INFLAMMATION 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

Although TRAIL-induced stimulation of c-Jun N-terminal kinase and p38 was caspase-dependent in a cell type-specific fashion, activation of nuclear factor kappaB and p42/44 was caspase-independent in all cases.

TRAIL Positive_regulation (stimulation) of c-Jun N-terminal kinase

1) Confidence 0.37 Published 2009 Journal FEBS J. Section Abstract Doc Link 19895579 Disease Relevance 1.03 Pain Relevance 0

Preceding cell death, TRAIL activated nuclear factor kappaB, c-Jun N-terminal kinase, p38 and p42/44.

TRAIL Positive_regulation (activated) of c-Jun N-terminal kinase associated with death

2) Confidence 0.37 Published 2009 Journal FEBS J. Section Abstract Doc Link 19895579 Disease Relevance 1.01 Pain Relevance 0

General Comments

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