INT16413

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Context Info
Confidence 0.43
First Reported 1991
Last Reported 1991
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.76
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nppa) nucleus (Nppa) cytoplasm (Nppa)
Anatomy Link Frequency
Brain 2
Nppa (Rattus norvegicus)
LH (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 3 96.96 Very High Very High Very High
Opioid 6 76.16 Quite High
antagonist 6 75.60 Quite High
narcan 12 74.64 Quite High
Dopamine 6 54.96 Quite High
Disease Link Frequency Relevance Heat
Natriuresis 9 99.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) are present in brain regions regulating LH secretion.
ANP Regulation (regulating) of Localization (secretion) of LH in Brain associated with natriuresis
1) Confidence 0.43 Published 1991 Journal Endocrinology Section Abstract Doc Link 1830270 Disease Relevance 0.27 Pain Relevance 0.04
This study examined the effects of centrally administered BNP and ANP on LH secretion in mature ovariectomized (OVX) rats.
ANP Spec (examined) Regulation (effects) of Localization (secretion) of LH
2) Confidence 0.43 Published 1991 Journal Endocrinology Section Abstract Doc Link 1830270 Disease Relevance 0.26 Pain Relevance 0.12
LH secretion was not affected by ANP or BNP at a lower concentration (0.2 nmol, icv; P greater than 0.05; n = 8/group).
ANP Neg (not) Regulation (affected) of Localization (secretion) of LH
3) Confidence 0.23 Published 1991 Journal Endocrinology Section Abstract Doc Link 1830270 Disease Relevance 0.23 Pain Relevance 0.29

General Comments

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