INT164150

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (S100a8, Trpv1) transport (Trpv1) transmembrane transport (Trpv1)
lipid metabolic process (Trpv1) cytoplasm (S100a8) cytosol (Trpv1)
Anatomy Link Frequency
bowel 1
S100a8 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 100.00 Very High Very High Very High
Neuropathic pain 1 97.84 Very High Very High Very High
c fibre 1 96.12 Very High Very High Very High
unmyelinated 1 95.76 Very High Very High Very High
primary afferent fibers 1 91.96 High High
Cannabinoid receptor 1 81.64 Quite High
qutenza 1 76.68 Quite High
antagonist 1 32.48 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 100.00 Very High Very High Very High
Neuropathic Pain 1 97.84 Very High Very High Very High
Arthritis 1 97.12 Very High Very High Very High
Inflammatory Bowel Disease 1 96.20 Very High Very High Very High
Sepsis 1 72.64 Quite High
Overactive Bladder 1 46.88 Quite Low
Neurodegenerative Disease 1 43.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Historically, TRPV1 has been considered as a pro-inflammatory receptor due to its key role in several conditions, including neuropathic pain, joint inflammation and inflammatory bowel disease, amongst others.
pro-inflammatory Binding (receptor) of TRPV1 in bowel associated with inflammation, neuropathic pain and arthritis
1) Confidence 0.04 Published 2010 Journal Pharmacol. Ther. Section Abstract Doc Link 19896501 Disease Relevance 0.60 Pain Relevance 0.62

General Comments

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