INT164220

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Context Info
Confidence 0.65
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 21
Total Number 21
Disease Relevance 13.70
Pain Relevance 4.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OPN1SW) plasma membrane (OPN1SW) signal transducer activity (OPN1SW)
Anatomy Link Frequency
superior 2
cerebral cortex 1
Appendix 1
OPN1SW (Homo sapiens)
Pain Link Frequency Relevance Heat
behavioral therapy 376 100.00 Very High Very High Very High
antidepressant 73 100.00 Very High Very High Very High
Pain management 16 99.52 Very High Very High Very High
Arthritis 86 99.28 Very High Very High Very High
cerebral cortex 4 97.04 Very High Very High Very High
Pain 229 93.84 High High
Lasting pain 42 89.28 High High
Serotonin 22 89.08 High High
sSRI 104 88.64 High High
monoamine 15 86.24 High High
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 55 99.80 Very High Very High Very High
Cognitive Disorder 204 99.76 Very High Very High Very High
Pain 279 99.52 Very High Very High Very High
Arthritis 86 99.28 Very High Very High Very High
Post-traumatic Stress Disorder 95 99.24 Very High Very High Very High
Fatigue 190 98.72 Very High Very High Very High
Depression 113 98.66 Very High Very High Very High
Sleep Disorders 75 98.20 Very High Very High Very High
Injury 75 97.92 Very High Very High Very High
Recurrence 76 97.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Imagery/hypnosis and CBT/CST interventions have produced improvement in all the three cancer-related symptoms individually: pain, fatigue, and sleep disturbance.
Gene_expression (/) of CBT
1) Confidence 0.65 Published 2010 Journal J Pain Symptom Manage Section Body Doc Link 19900778 Disease Relevance 0 Pain Relevance 0
In addition, the authors state that there appears to be robust and convergent metaanalytic evidence that CBT produces vastly superior long-term persistence of effects, with relapse rates half those of pharmacotherapy.
Gene_expression (produces) of CBT in superior associated with behavioral therapy and recurrence
2) Confidence 0.65 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 0.62 Pain Relevance 0.57
However, at the end of this transition period, CBT is falling and CBFV is still rising, perhaps reflecting continued activation of the cerebral cortex.
Gene_expression (falling) of CBT in cerebral cortex associated with cerebral cortex
3) Confidence 0.58 Published 2005 Journal J Circadian Rhythms Section Body Doc Link PMC555580 Disease Relevance 0.05 Pain Relevance 0.05
To align CBFV to the CBT circadian nadir as shown in Figure 3, the CBT nadir of each individual subject was set to circadian time 0, or 0°.
Gene_expression (nadir) of CBT
4) Confidence 0.58 Published 2005 Journal J Circadian Rhythms Section Body Doc Link PMC555580 Disease Relevance 0 Pain Relevance 0
CBFV rhythm is 90 degrees out of phase with the CBT rhythm
Gene_expression (rhythm) of CBT
5) Confidence 0.58 Published 2005 Journal J Circadian Rhythms Section Body Doc Link PMC555580 Disease Relevance 0 Pain Relevance 0
Each half hour data point after the CBT nadir and CBFV nadir were then set to a circadian degree.
Gene_expression (nadir) of CBT
6) Confidence 0.58 Published 2005 Journal J Circadian Rhythms Section Body Doc Link PMC555580 Disease Relevance 0 Pain Relevance 0
However, a review of the literature indicates only a handful of controlled trials that have been published examining TF-CBT for children with PTSD following a single-incident trauma.
Spec (examining) Gene_expression (examining) of TF-CBT associated with post-traumatic stress disorder and injury
7) Confidence 0.57 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2998467 Disease Relevance 0.82 Pain Relevance 0
In a recent review, Roy-Byrne et al (2006) concluded that the nature of the evidence concerning the efficacy of CBT is robust, but that CBT approaches are underused in most countries, compared with drug treatment.
Gene_expression (approaches) of CBT associated with behavioral therapy
8) Confidence 0.56 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 0.40 Pain Relevance 0.46
In a recent review, Roy-Byrne et al (2006) concluded that the nature of the evidence concerning the efficacy of CBT is robust, but that CBT approaches are underused in most countries, compared with drug treatment.
Gene_expression (approaches) of CBT associated with behavioral therapy
9) Confidence 0.56 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 0.46 Pain Relevance 0.46
Initial results of the study indicate that patients in the VRET and in the CBT groups improve significantly more than patients in the waiting list control group, and that there are no significant differences in outcome measures between patients treated by VRET and patients treated by exposure in vivo.
Gene_expression (groups) of CBT associated with behavioral therapy
10) Confidence 0.56 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 1.26 Pain Relevance 0.15
Combining pharmacotherapy with CBT has been found to be superior to antidepressant pharmacotherapy or CBT alone, but only in the acute-phase treatment.
Gene_expression (antidepressant) of CBT in superior associated with antidepressant
11) Confidence 0.56 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Abstract Doc Link PMC2536545 Disease Relevance 0.80 Pain Relevance 0.22
Some pain management techniques, such as relaxation, may be taught in isolation, but this in itself does not comprise a program of CST or CBT.
Gene_expression (program) of CBT associated with behavioral therapy and pain management
12) Confidence 0.56 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794518 Disease Relevance 1.11 Pain Relevance 0.92
Other individualized or group specific educational programs may be designed by health care providers to match the needs of their audience, and may include elements similar in nature to the Arthritis Self Management Program or CST and CBT approaches.
Gene_expression (approaches) of CBT associated with behavioral therapy and arthritis
13) Confidence 0.56 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794518 Disease Relevance 0.99 Pain Relevance 0.73
Cognitive behavioral theory (CBT)
Gene_expression (theory) of CBT associated with cognitive disorder
14) Confidence 0.39 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC2915551 Disease Relevance 0.64 Pain Relevance 0.38
These changes, particularly the phase-delays achieved in CBT and TSH, as well as amplitude changes produced in CBT and PRL, indicate, that like light therapy, SD might achieve its mood elevating effects by targeting and correcting abnormal circadian rhythms.
Gene_expression (produced) of CBT associated with sleep disorders
15) Confidence 0.21 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 1.15 Pain Relevance 0
Lending further support to the idea that PMDD women experience a phase-advance of circadian rhythms similar to what is observed in MDD [108], these women also experienced a tendency for phase-advanced CBT rhythms as well as significantly advanced melatonin and TSH when compared with controls (Table 2).
Gene_expression (rhythms) of CBT associated with depression and premenstrual syndrome
16) Confidence 0.19 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 0.90 Pain Relevance 0
Recently, the first randomised controlled trial (RCT) of an Internet-based CBT program for GAD was completed with results suggesting the Internet-based program, compared to a waitlist control, resulted in clinically significant reductions in worry and symptoms of anxiety.
Gene_expression (program) of CBT associated with generalized anxiety disorder and anxiety disorder
17) Confidence 0.17 Published 2010 Journal Trials Section Body Doc Link PMC2878300 Disease Relevance 1.35 Pain Relevance 0.04
Appendix 1: Overview of CBT intervention
Gene_expression (intervention) of CBT in Appendix
18) Confidence 0.11 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2821386 Disease Relevance 1.12 Pain Relevance 0.17
(4) What are patients' expectations of and experiences with exercise therapy and CBT?
Gene_expression (expectations) of CBT
19) Confidence 0.11 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2821386 Disease Relevance 1.05 Pain Relevance 0
The sample size was based on the detection of an approximately equal effect size of exercise training and CBT in comparison to usual care.
Gene_expression (detection) of CBT
20) Confidence 0.11 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2821386 Disease Relevance 0.70 Pain Relevance 0

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